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Substrate-binding Sites of UBR1, the Ubiquitin Ligase of the N-end Rule Pathway
Substrates of a ubiquitin-dependent proteolytic system called the N-end rule pathway include proteins with destabilizing N-terminal residues. N-recognins, the pathway's ubiquitin ligases, contain three substrate-binding sites. The type-1 site is specific for basic N-terminal residues (Arg, Lys,...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527112/ https://ncbi.nlm.nih.gov/pubmed/18566452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802583200 |
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