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Female Lethality and Apoptosis of Spermatocytes in Mice Lacking the UBR2 Ubiquitin Ligase of the N-End Rule Pathway
Substrates of the ubiquitin-dependent N-end rule pathway include proteins with destabilizing N-terminal residues. UBR1(−/−) mice, which lacked the pathway's ubiquitin ligase E3α, were viable and retained the N-end rule pathway. The present work describes the identification and analysis of mouse...
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| Huvudupphovsmän: | , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC262401/ https://ncbi.nlm.nih.gov/pubmed/14585983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.22.8255-8271.2003 |
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