Female Lethality and Apoptosis of Spermatocytes in Mice Lacking the UBR2 Ubiquitin Ligase of the N-End Rule Pathway
Substrates of the ubiquitin-dependent N-end rule pathway include proteins with destabilizing N-terminal residues. UBR1(−/−) mice, which lacked the pathway's ubiquitin ligase E3α, were viable and retained the N-end rule pathway. The present work describes the identification and analysis of mouse UBR2...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262401/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14585983/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.22.8255-8271.2003 |
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