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An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes
INTRODUCTION: Cells synthesize glucose if deprived of it, and destroy gluconeogenic enzymes upon return to glucose-replete conditions. Gluconeogenesis (de novo synthesis of glucose) is, in effect, a reversal of glycolysis, in which glucose is converted to pyruvate. Some enzymatic steps are shared be...
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| Publicado no: | Science |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5457285/ https://ncbi.nlm.nih.gov/pubmed/28126757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aal3655 |
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