Topoisomerase I interaction with SV40 DNA in the presence and absence of camptothecin.
Camptothecin is an antitumor drug, which is a specific inhibitor of eukaryotic topoisomerase I. Enzyme inhibition is related to the stabilization of cleavable complexes between topoisomerase I and DNA. The genomic and DNA sequence localization of L1210 topoisomerase I-mediated DNA breaks produced by...
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| Publicado en: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1988
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2849758/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.23.11157 |
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