Topoisomerase I interaction with SV40 DNA in the presence and absence of camptothecin.

Camptothecin is an antitumor drug, which is a specific inhibitor of eukaryotic topoisomerase I. Enzyme inhibition is related to the stabilization of cleavable complexes between topoisomerase I and DNA. The genomic and DNA sequence localization of L1210 topoisomerase I-mediated DNA breaks produced by...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Jaxel, C, Kohn, K W, Pommier, Y
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1988
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339002/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2849758/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.23.11157
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