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Topoisomerase I interaction with SV40 DNA in the presence and absence of camptothecin.
Camptothecin is an antitumor drug, which is a specific inhibitor of eukaryotic topoisomerase I. Enzyme inhibition is related to the stabilization of cleavable complexes between topoisomerase I and DNA. The genomic and DNA sequence localization of L1210 topoisomerase I-mediated DNA breaks produced by...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1988
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC339002/ https://ncbi.nlm.nih.gov/pubmed/2849758 |
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