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Topoisomerase I interaction with SV40 DNA in the presence and absence of camptothecin.

Camptothecin is an antitumor drug, which is a specific inhibitor of eukaryotic topoisomerase I. Enzyme inhibition is related to the stabilization of cleavable complexes between topoisomerase I and DNA. The genomic and DNA sequence localization of L1210 topoisomerase I-mediated DNA breaks produced by...

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Detaylı Bibliyografya
Asıl Yazarlar: Jaxel, C, Kohn, K W, Pommier, Y
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1988
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC339002/
https://ncbi.nlm.nih.gov/pubmed/2849758
Etiketler: Etiketle
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