Llwytho...

SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling

Amino acids stimulate cell growth and suppress autophagy through activation of mTORC1. The activation of mTORC1 by amino acids is mediated by Rag guanosine triphosphatase (GTPase) heterodimers on the lysosome. The molecular mechanism by which amino acids regulate the Rag GTPase heterodimers remains...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Young-Mi, Stone, Matthew, Hwang, Tae Hyun, Kim, Yeon-Gil, Dunlevy, Jane R., Griffin, Timothy J., Kim, Do-Hyung
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389276/
https://ncbi.nlm.nih.gov/pubmed/22575674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.04.007
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