Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade

The transthyretin amyloidoses (ATTR) are invariably fatal diseases characterized by progressive neuropathy and/or cardiomyopathy. ATTR are caused by aggregation of transthyretin (TTR), a natively tetrameric protein involved in the transport of thyroxine and the vitamin A–retinol-binding protein comp...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bulawa, Christine E., Connelly, Stephen, DeVit, Michael, Wang, Lan, Weigel, Charlotte, Fleming, James A., Packman, Jeff, Powers, Evan T., Wiseman, R. Luke, Foss, Theodore R., Wilson, Ian A., Kelly, Jeffery W., Labaudinière, Richard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386102/
https://ncbi.nlm.nih.gov/pubmed/22645360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121005109
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