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The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes

GW182 family proteins are essential for miRNA-mediated gene silencing in animal cells. They are recruited to miRNA targets via interactions with Argonaute proteins and then promote translational repression and degradation of the miRNA targets. The human and Drosophila melanogaster GW182 proteins sha...

詳細記述

保存先:
書誌詳細
主要な著者: Kuzuoğlu-Öztürk, Duygu, Huntzinger, Eric, Schmidt, Steffen, Izaurralde, Elisa
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2012
主題:
RNA
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384334/
https://ncbi.nlm.nih.gov/pubmed/22402495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks218
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