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The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes

GW182 family proteins are essential for miRNA-mediated gene silencing in animal cells. They are recruited to miRNA targets via interactions with Argonaute proteins and then promote translational repression and degradation of the miRNA targets. The human and Drosophila melanogaster GW182 proteins sha...

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Autors principals: Kuzuoğlu-Öztürk, Duygu, Huntzinger, Eric, Schmidt, Steffen, Izaurralde, Elisa
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
RNA
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384334/
https://ncbi.nlm.nih.gov/pubmed/22402495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks218
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