AMP-dependent DNA relaxation catalyzed by DNA ligase occurs by a nicking-closing mechanism.
In the presence of AMP and Mg2+, a covalently closed duplex DNA containing negative superhelical turns was treated with DNA ligase isolated from bacteriophage T4-infected E. coli. This resulted in the gradual and not sudden loss of superhelical turns as for example in the case of type I DNA topoisom...
Tallennettuna:
| Julkaisussa: | Nucleic Acids Res |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
1988
|
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC338414/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3137526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.15.7369 |
| Tagit: |
Ei tageja, Lisää ensimmäinen tagi!
|