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DNA unwinding and inhibition of T4 DNA ligase by anthracyclines.

The ability to alter DNA tertiary structure of ten anthracycline derivatives whose antitumor potency is known was studied by an assay that makes use of nicked circular DNA and bacteriophage T4 DNA ligase. This assay allows the detection of tertiary structure alterations caused by DNA binding of both...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Montecucco, A, Pedrali-Noy, G, Spadari, S, Zanolin, E, Ciarrocchi, G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1988
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC336564/
https://ncbi.nlm.nih.gov/pubmed/3287337
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