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DNA unwinding and inhibition of T4 DNA ligase by anthracyclines.

The ability to alter DNA tertiary structure of ten anthracycline derivatives whose antitumor potency is known was studied by an assay that makes use of nicked circular DNA and bacteriophage T4 DNA ligase. This assay allows the detection of tertiary structure alterations caused by DNA binding of both...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Montecucco, A, Pedrali-Noy, G, Spadari, S, Zanolin, E, Ciarrocchi, G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 1988
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336564/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3287337/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.9.3907
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