Loading...

DNA unwinding and inhibition of T4 DNA ligase by anthracyclines.

The ability to alter DNA tertiary structure of ten anthracycline derivatives whose antitumor potency is known was studied by an assay that makes use of nicked circular DNA and bacteriophage T4 DNA ligase. This assay allows the detection of tertiary structure alterations caused by DNA binding of both...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Montecucco, A, Pedrali-Noy, G, Spadari, S, Zanolin, E, Ciarrocchi, G
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC336564/
https://ncbi.nlm.nih.gov/pubmed/3287337
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!