DNA unwinding and inhibition of T4 DNA ligase by anthracyclines.
The ability to alter DNA tertiary structure of ten anthracycline derivatives whose antitumor potency is known was studied by an assay that makes use of nicked circular DNA and bacteriophage T4 DNA ligase. This assay allows the detection of tertiary structure alterations caused by DNA binding of both...
Gardado en:
| Publicado en: | Nucleic Acids Res |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1988
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3287337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.9.3907 |
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