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Specific interactions of distamycin with G-quadruplex DNA

Distamycin binds the minor groove of duplex DNA at AT-rich regions and has been a valuable probe of protein interactions with double-stranded DNA. We find that distamycin can also inhibit protein interactions with G-quadruplex (G4) DNA, a stable four-stranded structure in which the repeating unit is...

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Sonraí Bibleagrafaíochta
Main Authors: Cocco, Melanie J., Hanakahi, L. A., Huber, Michael D., Maizels, Nancy
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC156726/
https://ncbi.nlm.nih.gov/pubmed/12771220
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