Specific inhibition of human DNA ligase adenylation by a distamycin derivative possessing antitumor activity.

The antiviral distamycin A and its phenyl mustard derivative FCE24517 possessing antitumor activity were tested for their ability to inhibit macromolecular synthesis in three human and one murine cell line. While distamycin A was poorly active in these systems, FCE24517 inhibited DNA synthesis effic...

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Podrobná bibliografie

Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Montecucco, A, Fontana, M, Focher, F, Lestingi, M, Spadari, S, Ciarrocchi, G
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1991
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1708493/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.5.1067
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