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Specific inhibition of human DNA ligase adenylation by a distamycin derivative possessing antitumor activity.
The antiviral distamycin A and its phenyl mustard derivative FCE24517 possessing antitumor activity were tested for their ability to inhibit macromolecular synthesis in three human and one murine cell line. While distamycin A was poorly active in these systems, FCE24517 inhibited DNA synthesis effic...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1991
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC333782/ https://ncbi.nlm.nih.gov/pubmed/1708493 |
| Etiquetas: |
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