Specific inhibition of human DNA ligase adenylation by a distamycin derivative possessing antitumor activity.
The antiviral distamycin A and its phenyl mustard derivative FCE24517 possessing antitumor activity were tested for their ability to inhibit macromolecular synthesis in three human and one murine cell line. While distamycin A was poorly active in these systems, FCE24517 inhibited DNA synthesis effic...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1991
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| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1708493/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.5.1067 |
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