Specific inhibition of human DNA ligase adenylation by a distamycin derivative possessing antitumor activity.

The antiviral distamycin A and its phenyl mustard derivative FCE24517 possessing antitumor activity were tested for their ability to inhibit macromolecular synthesis in three human and one murine cell line. While distamycin A was poorly active in these systems, FCE24517 inhibited DNA synthesis effic...

Descripció completa

Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Montecucco, A, Fontana, M, Focher, F, Lestingi, M, Spadari, S, Ciarrocchi, G
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1991
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1708493/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.5.1067
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!