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Multiple Phenotypes in Huntington Disease Mouse Neural Stem Cells

Neural stem (NS) cells are a limitless resource, and thus superior to primary neurons for drug discovery provided they exhibit appropriate disease phenotypes. Here we established NS cells for cellular studies of Huntington’s disease (HD). HD is a heritable neurodegenerative disease caused by a mutat...

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Detaylı Bibliyografya
Asıl Yazarlar: Ritch, James J., Valencia, Antonio, Alexander, Jonathan, Sapp, Ellen, Gatune, Leah, Sangrey, Gavin R., Sinha, Saurabh, Scherber, Cally M., Zeitlin, Scott, Sadri-Vakili, Ghazaleh, Irimia, Daniel, DiFiglia, Marian, Kegel, Kimberly B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383872/
https://ncbi.nlm.nih.gov/pubmed/22508027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.03.011
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