Multiple Phenotypes in Huntington Disease Mouse Neural Stem Cells

Neural stem (NS) cells are a limitless resource, and thus superior to primary neurons for drug discovery provided they exhibit appropriate disease phenotypes. Here we established NS cells for cellular studies of Huntington’s disease (HD). HD is a heritable neurodegenerative disease caused by a mutat...

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Hlavní autoři: Ritch, James J., Valencia, Antonio, Alexander, Jonathan, Sapp, Ellen, Gatune, Leah, Sangrey, Gavin R., Sinha, Saurabh, Scherber, Cally M., Zeitlin, Scott, Sadri-Vakili, Ghazaleh, Irimia, Daniel, DiFiglia, Marian, Kegel, Kimberly B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383872/
https://ncbi.nlm.nih.gov/pubmed/22508027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.03.011
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