Differential requirement of RasGRP1 for γδ T cell development and activation

γδ T cells (γδT) belong to a distinct T cell lineage that performs immune functions different from αβ T cells (αβT). Previous studies have established that Erk1/2 MAPKs are critical for positive selection of αβT cells. Additional evidence also suggests that elevated Erk1/2 activity promotes γδT cell...

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Main Authors: Chen, Yong, Ci, Xinxin, Gorentla, Balachandra, Sullivan, Sarah A., Stone, James C., Zhang, Weiguo, Pereira, Pablo, Lu, Jianxin, Zhong, Xiao-Ping
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382004/
https://ncbi.nlm.nih.gov/pubmed/22623331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103272
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