Critical roles of RasGRP1 for invariant natural killer T cell development

The invariant NKT (iNKT) cell lineage contains CD4(+) and CD4(-) subsets. The mechanisms that control such subset differentiation and iNKT cell maturation in general have not been fully understood. RasGRP1, a guanine nucleotide exchange factor for T cell receptor-induced activation of the Ras-Erk1/2...

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Bibliographic Details
Main Authors: Shen, Shudan, Chen, Yong, Gorentla, Balachandra, Lu, Jianxin, Stone, James C., Zhong, Xiao-Ping
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212869/
https://ncbi.nlm.nih.gov/pubmed/21957144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003798
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