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Differential requirement of RasGRP1 for γδ T cell development and activation
γδ T cells (γδT) belong to a distinct T cell lineage that performs immune functions different from αβ T cells (αβT). Previous studies have established that Erk1/2 MAPKs are critical for positive selection of αβT cells. Additional evidence also suggests that elevated Erk1/2 activity promotes γδT cell...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382004/ https://ncbi.nlm.nih.gov/pubmed/22623331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103272 |
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