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Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development
Type I natural killer T (NKT) cells, or iNKT cells, express a semi-invariant T cell receptor characterized by its unique V α 14-Jα 18 usage (iV α 14TCR). Upon interaction with glycolipid/CD1d complexes, the iV α 14TCRs transduce signals that are essential for iNKT selection and maturation. However,...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159847/ https://ncbi.nlm.nih.gov/pubmed/21775687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100495 |
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