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Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development

Type I natural killer T (NKT) cells, or iNKT cells, express a semi-invariant T cell receptor characterized by its unique V α 14-Jα 18 usage (iV α 14TCR). Upon interaction with glycolipid/CD1d complexes, the iV α 14TCRs transduce signals that are essential for iNKT selection and maturation. However,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Shen, Shudan, Wu, Jinhong, Srivatsan, Sruti, Gorentla, Balachandra, Shin, Jinwook, Xu, Li, Zhong, Xiao-Ping
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159847/
https://ncbi.nlm.nih.gov/pubmed/21775687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100495
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