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mTOR and its tight regulation for iNKT cell development and effector function

Invariant NKT (iNKT) cells, which express the invariant Vα14Jα18 TCR that recognizes lipid antigens, have the ability to rapidly respond to agonist stimulation, producing a variety of cytokines that can shape both innate and adaptive immunity. iNKT cells have been implicated in host defense against...

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Détails bibliographiques
Publié dans:Mol Immunol
Auteurs principaux: Yang, Wei, Gorentla, Balachandra, Zhong, Xiao-Ping, Shin, Jinwook
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679438/
https://ncbi.nlm.nih.gov/pubmed/26253278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2015.07.022
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