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TSC1 promotes iNKT cell anergy and inhibits iNKT cell-mediated anti-tumor immunity

Development of effective immune therapies for cancer patients requires better understanding of hurdles that prevent the generation of effective anti-tumor immune responses. Administration of α-galactosylceramide (α-GalCer) in animals enhances anti-tumor immunity via activation of the invariant natur...

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Detalhes bibliográficos
Main Authors: Wu, Jinhong, Shin, Jinwook, Xie, Danli, Wang, Hongxia, Gao, Jimin, Zhong, Xiao-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965184/
https://ncbi.nlm.nih.gov/pubmed/24532578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302076
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