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TSC1 promotes iNKT cell anergy and inhibits iNKT cell-mediated anti-tumor immunity

Development of effective immune therapies for cancer patients requires better understanding of hurdles that prevent the generation of effective anti-tumor immune responses. Administration of α-galactosylceramide (α-GalCer) in animals enhances anti-tumor immunity via activation of the invariant natur...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Jinhong, Shin, Jinwook, Xie, Danli, Wang, Hongxia, Gao, Jimin, Zhong, Xiao-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965184/
https://ncbi.nlm.nih.gov/pubmed/24532578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302076
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