A Hybrid CFHR3-1 Gene Causes Familial C3 Glomerulopathy

Controlled activation of the complement system, a key component of innate immunity, enables destruction of pathogens with minimal damage to host tissue. Complement factor H (CFH), which inhibits complement activation, and five CFH-related proteins (CFHR1–5) compose a family of structurally related m...

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Detalhes bibliográficos
Main Authors: Malik, Talat H., Lavin, Peter J., Goicoechea de Jorge, Elena, Vernon, Katherine A., Rose, Kirsten L., Patel, Mitali P., de Leeuw, Marcel, Neary, John J., Conlon, Peter J., Winn, Michelle P., Pickering, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380655/
https://ncbi.nlm.nih.gov/pubmed/22626820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012020166
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