Therapeutic targets in focal and segmental glomerulosclerosis

Por Lavin, Peter J., Gbadegesin, Rasheed, Damodaran, Tirupapuliyur V., Winn, Michelle P.
Publicado em 2008

EXCLUSION OF HOMOZYGOUS PLCE1 (NPHS3) MUTATIONS IN 69 FAMILIES WITH IDIOPATHIC AND HEREDITARY FSGS

Por Gbadegesin, Rasheed, Bartkowiak, Bartlomiej, Lavin, Peter J, Mukerji, Nirvan, Wu, Guanghong, Bowling, Brandy, Eckel, Jason, Damodaran, Tirupapuliyur, Winn, Michelle P
Publicado em 2008

Hepatorenal Correction in Murine Glycogen Storage Disease Type I With a Double-stranded Adeno-associated Virus Vector

Por Luo, Xiaoyan, Hall, Gentzon, Li, Songtao, Bird, Andrew, Lavin, Peter J, Winn, Michelle P, Kemper, Alex R, Brown, Talmage T, Koeberl, Dwight D
Publicado em 2011

Gq signaling causes glomerular injury by activating TRPC6

Por Wang, Liming, Jirka, Grant, Rosenberg, Paul B., Buckley, Anne F., Gomez, Jose A., Fields, Timothy A., Winn, Michelle P., Spurney, Robert F.
Publicado no J Clin Invest (2015)

Variability in phenotype induced by the podocin variant R229Q plus a single pathogenic mutation

Por Phelan, Paul J., Hall, Gentzon, Wigfall, Delbert, Foreman, John, Nagaraj, Shashi, Malone, Andrew F., Winn, Michelle P., Howell, David N., Gbadegesin, Rasheed
Publicado no Clin Kidney J (2015)

Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis

Por Akilesh, Shreeram, Suleiman, Hani, Yu, Haiyang, Stander, M. Christine, Lavin, Peter, Gbadegesin, Rasheed, Antignac, Corinne, Pollak, Martin, Kopp, Jeffrey B., Winn, Michelle P., Shaw, Andrey S.
Publicado em 2011

A New Locus for Familial FSGS on Chromosome 2P

Por Gbadegesin, Rasheed, Lavin, Peter, Janssens, Louis, Bartkowiak, Bartlomiej, Homstad, Alison, Wu, Guanghong, Bowling, Brandy, Eckel, Jason, Potocky, Chris, Abbott, Diana, Conlon, Peter, Scott, William K., Howell, David, Hauser, Elizabeth, Winn, Michelle P.
Publicado em 2010

Modulation of the BP Response to Diet by Genes in the Renin–Angiotensin System and the Adrenergic Nervous System

Por Svetkey, Laura P., Harris, Emily L., Martin, Eden, Vollmer, William M., Meltesen, Gayle T., Ricchiuti, Vincent, Williams, Gordon, Appel, Lawrence J., Bray, George A., Moore, Thomas J., Winn, Michelle P., Conlin, Paul R.
Publicado em 2010

INVERTED FORMIN 2 MUTATIONS WITH VARIABLE EXPRESION IN PATIENTS WITH SPORADIC AND HEREDITARY FOCAL AND SEGMENTAL GLOMERULOSCLEROSIS

Por Gbadegesin, Rasheed, Lavin, Peter J., Hall, Gentzon, Bartkowiak, B, Homstad, A, Jiang, R, Wu, G, Byrd, A, Lynn, Kelvin, Wolfish, Norman, Ottati, Carolina, Stevens, Paul, Howell, David, Conlon, Peter, Winn, Michelle P.
Publicado em 2011

Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity

Por Hall, Gentzon, Rowell, Janelle, Farinelli, Federica, Gbadegesin, Rasheed A., Lavin, Peter, Wu, Guanghong, Homstad, Alison, Malone, Andrew, Lindsey, Thomas, Jiang, Ruiji, Spurney, Robert, Tomaselli, Gordon F., Kass, David A., Winn, Michelle P.
Publicado em 2014

A Hybrid CFHR3-1 Gene Causes Familial C3 Glomerulopathy

Por Malik, Talat H., Lavin, Peter J., Goicoechea de Jorge, Elena, Vernon, Katherine A., Rose, Kirsten L., Patel, Mitali P., de Leeuw, Marcel, Neary, John J., Conlon, Peter J., Winn, Michelle P., Pickering, Matthew C.
Publicado em 2012

TRPC6 Enhances Angiotensin II-induced Albuminuria

Por Eckel, Jason, Lavin, Peter J., Finch, Elizabeth A., Mukerji, Nirvan, Burch, Jarrett, Gbadegesin, Rasheed, Wu, Guanghong, Bowling, Brandy, Byrd, Alison, Hall, Gentzon, Sparks, Matthew, Zhang, Zhu Shan, Homstad, Alison, Barisoni, Laura, Birbaumer, Lutz, Rosenberg, Paul, Winn, Michelle P.
Publicado em 2011

Screening for NPHS2 Mutations May Help Predict FSGS Recurrence after Transplantation

Por Jungraithmayr, Therese C., Hofer, Katrin, Cochat, Pierre, Chernin, Gil, Cortina, Gerard, Fargue, Sonja, Grimm, Paul, Knueppel, Tanja, Kowarsch, Andreas, Neuhaus, Thomas, Pagel, Philipp, Pfeiffer, Karl P., Schäfer, Franz, Schönermarck, Ulf, Seeman, Tomas, Toenshoff, Burkhard, Weber, Stefanie, Winn, Michelle P., Zschocke, Johannes, Zimmerhackl, Lothar B.
Publicado em 2011

A Novel Missense Mutation of Wilms’ Tumor 1 Causes Autosomal Dominant FSGS

Por Hall, Gentzon, Gbadegesin, Rasheed A., Lavin, Peter, Wu, Guanghong, Liu, Yangfan, Oh, Edwin C., Wang, Liming, Spurney, Robert F., Eckel, Jason, Lindsey, Thomas, Homstad, Alison, Malone, Andrew F., Phelan, Paul J., Shaw, Andrey, Howell, David N., Conlon, Peter J., Katsanis, Nicholas, Winn, Michelle P.
Publicado no J Am Soc Nephrol (2015)

TNXB Mutations Can Cause Vesicoureteral Reflux

Por Gbadegesin, Rasheed A., Brophy, Patrick D., Adeyemo, Adebowale, Hall, Gentzon, Gupta, Indra R., Hains, David, Bartkowiak, Bartlomeij, Rabinovich, C. Egla, Chandrasekharappa, Settara, Homstad, Alison, Westreich, Katherine, Wu, Guanghong, Liu, Yutao, Holanda, Danniele, Clarke, Jason, Lavin, Peter, Selim, Angelica, Miller, Sara, Wiener, John S., Ross, Sherry S., Foreman, John, Rotimi, Charles, Winn, Michelle P.
Publicado em 2013

Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis

Por Malone, Andrew F, Phelan, Paul J, Hall, Gentzon, Cetincelik, Umran, Homstad, Alison, Alonso, Andrea, Jiang, Ruiji, Lindsey, Thomas, Wu, Guanghong, Sparks, Matthew A, Smith, Stephen R, Webb, Nicholas J A, Kalra, Philip, Adeyemo, Adebowale, Shaw, Andrey S, Conlon, Peter J, Jennette, J Charles, Howell, David N, Winn, Michelle P, Gbadegesin, Rasheed A
Publicado no Kidney Int (2014)

Mutations in the Gene That Encodes the F-Actin Binding Protein Anillin Cause FSGS

Por Gbadegesin, Rasheed A., Hall, Gentzon, Adeyemo, Adebowale, Hanke, Nils, Tossidou, Irini, Burchette, James, Wu, Guanghong, Homstad, Alison, Sparks, Matthew A., Gomez, Jose, Jiang, Ruiji, Alonso, Andrea, Lavin, Peter, Conlon, Peter, Korstanje, Ron, Stander, M. Christine, Shamsan, Ghaidan, Barua, Moumita, Spurney, Robert, Singhal, Pravin C., Kopp, Jeffrey B., Haller, Hermann, Howell, David, Pollak, Martin R., Shaw, Andrey S., Schiffer, Mario, Winn, Michelle P.
Publicado em 2014

HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome

Por Gbadegesin, Rasheed A., Adeyemo, Adebowale, Webb, Nicholas J.A., Greenbaum, Larry A., Abeyagunawardena, Asiri, Thalgahagoda, Shenal, Kale, Arundhati, Gipson, Debbie, Srivastava, Tarak, Lin, Jen-Jar, Chand, Deepa, Hunley, Tracy E., Brophy, Patrick D., Bagga, Arvind, Sinha, Aditi, Rheault, Michelle N., Ghali, Joanna, Nicholls, Kathy, Abraham, Elizabeth, Janjua, Halima S., Omoloja, Abiodun, Barletta, Gina-Marie, Cai, Yi, Milford, David D., O'Brien, Catherine, Awan, Atif, Belostotsky, Vladimir, Smoyer, William E., Homstad, Alison, Hall, Gentzon, Wu, Guanghong, Nagaraj, Shashi, Wigfall, Delbert, Foreman, John, Winn, Michelle P.
Publicado no J Am Soc Nephrol (2015)