A Hybrid CFHR3-1 Gene Causes Familial C3 Glomerulopathy

Controlled activation of the complement system, a key component of innate immunity, enables destruction of pathogens with minimal damage to host tissue. Complement factor H (CFH), which inhibits complement activation, and five CFH-related proteins (CFHR1–5) compose a family of structurally related m...

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Bibliographische Detailangaben
Hauptverfasser: Malik, Talat H., Lavin, Peter J., Goicoechea de Jorge, Elena, Vernon, Katherine A., Rose, Kirsten L., Patel, Mitali P., de Leeuw, Marcel, Neary, John J., Conlon, Peter J., Winn, Michelle P., Pickering, Matthew C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2012
Schlagworte:
Brief Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380655/
https://ncbi.nlm.nih.gov/pubmed/22626820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012020166
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