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A Hybrid CFHR3-1 Gene Causes Familial C3 Glomerulopathy

Controlled activation of the complement system, a key component of innate immunity, enables destruction of pathogens with minimal damage to host tissue. Complement factor H (CFH), which inhibits complement activation, and five CFH-related proteins (CFHR1–5) compose a family of structurally related m...

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Библиографические подробности
Главные авторы: Malik, Talat H., Lavin, Peter J., Goicoechea de Jorge, Elena, Vernon, Katherine A., Rose, Kirsten L., Patel, Mitali P., de Leeuw, Marcel, Neary, John J., Conlon, Peter J., Winn, Michelle P., Pickering, Matthew C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380655/
https://ncbi.nlm.nih.gov/pubmed/22626820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012020166
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