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A Hybrid CFHR3-1 Gene Causes Familial C3 Glomerulopathy
Controlled activation of the complement system, a key component of innate immunity, enables destruction of pathogens with minimal damage to host tissue. Complement factor H (CFH), which inhibits complement activation, and five CFH-related proteins (CFHR1–5) compose a family of structurally related m...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Nephrology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380655/ https://ncbi.nlm.nih.gov/pubmed/22626820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012020166 |
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