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A Hybrid CFHR3-1 Gene Causes Familial C3 Glomerulopathy

Controlled activation of the complement system, a key component of innate immunity, enables destruction of pathogens with minimal damage to host tissue. Complement factor H (CFH), which inhibits complement activation, and five CFH-related proteins (CFHR1–5) compose a family of structurally related m...

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Bibliografiset tiedot
Päätekijät: Malik, Talat H., Lavin, Peter J., Goicoechea de Jorge, Elena, Vernon, Katherine A., Rose, Kirsten L., Patel, Mitali P., de Leeuw, Marcel, Neary, John J., Conlon, Peter J., Winn, Michelle P., Pickering, Matthew C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380655/
https://ncbi.nlm.nih.gov/pubmed/22626820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012020166
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