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Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy

The complement–mediated renal diseases C3 glomerulopathy (C3G) and atypical hemolytic uremic syndrome (aHUS) strongly associate with inherited and acquired abnormalities in the regulation of the complement alternative pathway (AP). The major negative regulator of the AP is the plasma protein complem...

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Podrobná bibliografie
Vydáno v:J Am Soc Nephrol
Hlavní autoři: Vernon, Katherine A., Ruseva, Marieta M., Cook, H. Terence, Botto, Marina, Malik, Talat H., Pickering, Matthew C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849824/
https://ncbi.nlm.nih.gov/pubmed/26374608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015030295
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