Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy

The complement–mediated renal diseases C3 glomerulopathy (C3G) and atypical hemolytic uremic syndrome (aHUS) strongly associate with inherited and acquired abnormalities in the regulation of the complement alternative pathway (AP). The major negative regulator of the AP is the plasma protein complem...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Vernon, Katherine A., Ruseva, Marieta M., Cook, H. Terence, Botto, Marina, Malik, Talat H., Pickering, Matthew C.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2016
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849824/
https://ncbi.nlm.nih.gov/pubmed/26374608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015030295
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