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Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy

The complement–mediated renal diseases C3 glomerulopathy (C3G) and atypical hemolytic uremic syndrome (aHUS) strongly associate with inherited and acquired abnormalities in the regulation of the complement alternative pathway (AP). The major negative regulator of the AP is the plasma protein complem...

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Dettagli Bibliografici
Pubblicato in:J Am Soc Nephrol
Autori principali: Vernon, Katherine A., Ruseva, Marieta M., Cook, H. Terence, Botto, Marina, Malik, Talat H., Pickering, Matthew C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849824/
https://ncbi.nlm.nih.gov/pubmed/26374608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015030295
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