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Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy

The complement–mediated renal diseases C3 glomerulopathy (C3G) and atypical hemolytic uremic syndrome (aHUS) strongly associate with inherited and acquired abnormalities in the regulation of the complement alternative pathway (AP). The major negative regulator of the AP is the plasma protein complem...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Am Soc Nephrol
Päätekijät: Vernon, Katherine A., Ruseva, Marieta M., Cook, H. Terence, Botto, Marina, Malik, Talat H., Pickering, Matthew C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849824/
https://ncbi.nlm.nih.gov/pubmed/26374608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015030295
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