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Complement receptor 3 mediates renal protection in experimental C3 glomerulopathy

C3 glomerulopathy is a complement-mediated renal disease that is frequently associated with abnormalities in regulation of the complement alternative pathway. Mice with deficiency of factor H (Cfh(–/–)), a negative alternative pathway regulator, are an established experimental model of C3 glomerulop...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Barbour, Thomas D., Ling, Guang Sheng, Ruseva, Marieta M., Fossati-Jimack, Liliane, Cook, H. Terence, Botto, Marina, Pickering, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869622/
https://ncbi.nlm.nih.gov/pubmed/26924054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2015.11.024
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