A Hybrid CFHR3-1 Gene Causes Familial C3 Glomerulopathy

Controlled activation of the complement system, a key component of innate immunity, enables destruction of pathogens with minimal damage to host tissue. Complement factor H (CFH), which inhibits complement activation, and five CFH-related proteins (CFHR1–5) compose a family of structurally related m...

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Detalles Bibliográficos
Autores principales: Malik, Talat H., Lavin, Peter J., Goicoechea de Jorge, Elena, Vernon, Katherine A., Rose, Kirsten L., Patel, Mitali P., de Leeuw, Marcel, Neary, John J., Conlon, Peter J., Winn, Michelle P., Pickering, Matthew C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2012
Materias:
Brief Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380655/
https://ncbi.nlm.nih.gov/pubmed/22626820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012020166
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