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Podocyte-Specific Loss of Cdc42 Leads to Congenital Nephropathy

Rho family GTPases are molecular switches best known for their pivotal role in dynamic regulation of the actin cytoskeleton. The prototypic members of this family are Cdc42, Rac1, and RhoA; these GTPases contribute to the breakdown of glomerular filtration and the resultant proteinuria, but their fu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Scott, Rizaldy P., Hawley, Steve P., Ruston, Julie, Du, Jianmei, Brakebusch, Cord, Jones, Nina, Pawson, Tony
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380653/
https://ncbi.nlm.nih.gov/pubmed/22518006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121206
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