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Podocyte-Specific Loss of Cdc42 Leads to Congenital Nephropathy

Rho family GTPases are molecular switches best known for their pivotal role in dynamic regulation of the actin cytoskeleton. The prototypic members of this family are Cdc42, Rac1, and RhoA; these GTPases contribute to the breakdown of glomerular filtration and the resultant proteinuria, but their fu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Scott, Rizaldy P., Hawley, Steve P., Ruston, Julie, Du, Jianmei, Brakebusch, Cord, Jones, Nina, Pawson, Tony
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Nephrology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380653/
https://ncbi.nlm.nih.gov/pubmed/22518006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121206
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