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Bromopyridazinedione-mediated protein and peptide bioconjugation
Bromopyridazinedione-mediated bioconjugation to a cysteine containing protein and a disulfide containing peptide is described. The conjugates are cleavable in an excess of thiol, including cytoplasmically-relevant concentrations of glutathione, and show a high level of hydrolytic stability. The cons...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Royal Society of Chemistry
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3379626/ https://ncbi.nlm.nih.gov/pubmed/21738916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc12807h |
| Oznake: |
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