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Rapid Identification of Orexin Receptor Binding Ligands Using Cell-Based Screening Accelerated with Magnetic Beads
We report here a simple and rapid method by which to screen one bead one compound libraries for highly specific ligands to cell surface proteins such as G protein-coupled receptors. This protocol, which harvests “hits” in a cell-based binding screen magnetically, eliminates the most tedious aspects...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3379552/ https://ncbi.nlm.nih.gov/pubmed/20024071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b915611a |
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