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On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands

Combinatorial library screens can identify a suitable ligand for a biological target of interest out of thousands or even millions of compounds, and can play a key role in the modern drug development process. While conventional high-throughput cell screens based on functional assays require expensiv...

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Detalhes bibliográficos
Main Authors: Udugamasooriya, D. Gomika, Kodadek, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348698/
https://ncbi.nlm.nih.gov/pubmed/22582145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470559277.ch110199
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