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Rapid Identification of Orexin Receptor Binding Ligands Using Cell-Based Screening Accelerated with Magnetic Beads

We report here a simple and rapid method by which to screen one bead one compound libraries for highly specific ligands to cell surface proteins such as G protein-coupled receptors. This protocol, which harvests “hits” in a cell-based binding screen magnetically, eliminates the most tedious aspects...

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Bibliographic Details
Main Authors: Qi, Xin, Astle, John, Kodadek, Thomas
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379552/
https://ncbi.nlm.nih.gov/pubmed/20024071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b915611a
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