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DNA polymerase zeta is required for proliferation of normal mammalian cells
Unique among translesion synthesis (TLS) DNA polymerases, pol ζ is essential during embryogenesis. To determine whether pol ζ is necessary for proliferation of normal cells, primary mouse fibroblasts were established in which Rev3L could be conditionally inactivated by Cre recombinase. Cells were gr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378892/ https://ncbi.nlm.nih.gov/pubmed/22319213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks054 |
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