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PRAK suppresses oncogenic ras-induced hematopoietic cancer development by antagonizing the JNK pathway
The p38 MAPK pathway regulates multiple physiological and pathological processes, including cancer development. PRAK, a p38 substrate protein kinase, has previously been implicated in the suppression of skin carcinogenesis. In the current study, we demonstrate that PRAK deletion accelerates hematopo...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378811/ https://ncbi.nlm.nih.gov/pubmed/22665523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0576 |
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