A Posttranslational Modification Cascade Involving p38, Tip60 and PRAK Mediates Oncogene-Induced Senescence

Oncogene-induced senescence is an important tumor-suppressing defense mechanism. However, relatively little is known about the signaling pathway mediating the senescence response. Here, we demonstrate that a multifunctional acetyltransferase Tip60 plays an essential role in oncogenic ras-induced sen...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Zheng, Hui, Seit-Nebi, Alim, Han, Xuemei, Aslanian, Aaron, Tat, John, Liao, Rong, Yates, John R., Sun, Peiqing
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679363/
https://ncbi.nlm.nih.gov/pubmed/23685072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.04.013
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker