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p38α and p38γ Mediate Oncogenic ras-induced Senescence through Differential Mechanisms
Oncogene-induced senescence is a tumor-suppressive defense mechanism triggered upon activation of certain oncogenes in normal cells. Recently, the senescence response to oncogene activation has been shown to act as a bona fide barrier to cancer development in vivo. Multiple previous studies have imp...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670128/ https://ncbi.nlm.nih.gov/pubmed/19251701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808327200 |
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