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p38α and p38γ Mediate Oncogenic ras-induced Senescence through Differential Mechanisms

Oncogene-induced senescence is a tumor-suppressive defense mechanism triggered upon activation of certain oncogenes in normal cells. Recently, the senescence response to oncogene activation has been shown to act as a bona fide barrier to cancer development in vivo. Multiple previous studies have imp...

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מידע ביבליוגרפי
Main Authors: Kwong, Jinny, Hong, Lixin, Liao, Rong, Deng, Qingdong, Han, Jiahuai, Sun, Peiqing
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670128/
https://ncbi.nlm.nih.gov/pubmed/19251701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808327200
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