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Essential role of p38γ in K-Ras transformation independent of phosphorylation
MAPK cascades play the critical role in regulating Ras oncogene activity by phosphorylation-dependent mechanisms. Whereas the ERK MAPK pathway is required for Ras transformation, our previous works established that the p38 activity is inhibitory to Ras signaling in both experimental and ras-mutated...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1224721/ https://ncbi.nlm.nih.gov/pubmed/15851477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M500699200 |
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