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p38γ Mitogen-activated Protein Kinase Signals through Phosphorylating Its Phosphatase PTPH1 in Regulating Ras Protein Oncogenesis and Stress Response

Phosphatase plays a crucial role in determining cellular fate by inactivating its substrate kinase, but it is not known whether a kinase can vice versa phosphorylate its phosphatase to execute this function. Protein-tyrosine phosphatase H1 (PTPH1) is a specific phosphatase of p38γ mitogen-activated...

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Autors principals: Hou, Songwang, Suresh, Padmanaban S., Qi, Xiaomei, Lepp, Adrienne, Mirza, Shama P., Chen, Guan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431700/
https://ncbi.nlm.nih.gov/pubmed/22730326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.335794
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