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PTPH1 dephosphorylates and cooperates with p38γ MAPK to increase Ras oncogenesis through PDZ-mediated interaction
Protein phosphatases are believed to coordinate with kinases to execute biological functions and examples of such integrated activities however are still missing. In this report, we have identified PTPH1 (protein tyrosine phosphatase H1) as a specific phosphatase for p38γ MAPK (mitogen-activated pro...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848905/ https://ncbi.nlm.nih.gov/pubmed/20332238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3229 |
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